PGDLLA
PGDLLA

BioDegmer® PGDLLA Poly(glycolide-co-DL-lactide)

Poly(glycolide-co-lactide) (PGLA) is obtained by the ring-opening co-polymerization of glycolide (cyclic dimer of glycolic acid) and lactide (cyclic dimer of lactic acid) as monomers.
Since lactide has 3 optical isomer as L-lactide, D-lactide, and DL-lactide, the copolymer of glycolide and L-lactide is abbreviated to PGLA, while the copolymer of glycolide and DL-lactide is abbreviated to PGDLLA.

Chemical name
Poly(glycolic acid-co-DL-lactic acid)
Poly(glycolide-co-DL-lactide)
Poly[oxy(1-oxo-2-methylethylene)-co-oxy(1-oxoethylene)]
Poly[oxy(2-oxoethylene)-co-oxy(1-methyl-2-oxoethylene)]
Chemical formula
?(C2H2O2)n?(C3H4O2)m?
?O?CO?CH2?O?CO?CH(CH3)?
Formula weight
130.09874
CAS number
34346?01?5, 26780?50?7
PoLyInfo PID
P903770, P901010
Characteristics
Soluble into general organic solvents

Typical specification of PGDLLA

The following shows the specification example of our PGDLLA polymer (PGDLLA(25:75)) product.
Testing item
Specification
Identification
Same as the standard NMR spectrum of PGDLLA. Identification
Composition 
CGA:CLA =20:80 ? 30:70 (mol%)
Weight averaged
molecular weight(MW)
MW = 220,000 ? 280,000
Glass transition
point(Tg
Tg = 50 ? 60 (℃)
Particle size
Not passing 500 μm mesh screen.
Appearance
No contamination by foreign objects
Normal coloring (white or beige or ivory) (Sensory test with eye)
If you have the specific requirement for PGDLLA polymer, please feel free to ask us.

Potential application of PGDLLA

PGDLLA polymer mainly applied for GTR-membranes (porous membranes) for regeneration and adhesion of lost periodontal supporting tissues caused by periodontal disease. (GTR: Guided Tissue Regeneration)
Applicable examples of the medical device obtained from PGDLLA polymers are shown with color in follows: